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Elevation of NAD+ by nicotinamide riboside spares spinal cord tissue from injury and promotes locomotor recovery.
Exp Neurol. 2023 Oct;368:114479. doi: 10.1016/j.expneurol.2023.114479. Epub 2023 Jul 15.
Exp Neurol. 2023.
PMID: 37454712
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.
McConoughey SJ, Basso M, Niatsetskaya ZV, Sleiman SF, Smirnova NA, Langley BC, Mahishi L, Cooper AJ, Antonyak MA, Cerione RA, Li B, Starkov A, Chaturvedi RK, Beal MF, Coppola G, Geschwind DH, Ryu H, Xia L, Iismaa SE, Pallos J, Pasternack R, Hils M, Fan J, Raymond LA, Marsh JL, Thompson LM, Ratan RR.
McConoughey SJ, et al. Among authors: langley bc.
EMBO Mol Med. 2010 Sep;2(9):349-70. doi: 10.1002/emmm.201000084.
EMBO Mol Med. 2010.
PMID: 20665636
Free PMC article.
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Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration.
Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, Rohr J, Ratan RR.
Sleiman SF, et al. Among authors: langley bc.
J Neurosci. 2011 May 4;31(18):6858-70. doi: 10.1523/JNEUROSCI.0710-11.2011.
J Neurosci. 2011.
PMID: 21543616
Free PMC article.
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Functional differences in epigenetic modulators-superiority of mercaptoacetamide-based histone deacetylase inhibitors relative to hydroxamates in cortical neuron neuroprotection studies.
Kozikowski AP, Chen Y, Gaysin A, Chen B, D'Annibale MA, Suto CM, Langley BC.
Kozikowski AP, et al. Among authors: langley bc.
J Med Chem. 2007 Jun 28;50(13):3054-61. doi: 10.1021/jm070178x. Epub 2007 Jun 1.
J Med Chem. 2007.
PMID: 17539623
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